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Using light to observe and understand physiological processes

Hendrik completes his MSc

Hendrik's MSc project aimed to develop a Spectral Domain Optical Coherence Tomography (SD-OCT) system with a high-resolution sensitivity for analysing biofilms and biofilm phantoms. The development encompassed designing system optics, developing a LabVIEW program for system operation, and Python-based data processing. Experiments included micrometre-scale measurements within biofilm growth enclosures, Doppler velocimetry of fluid flow through microfluidic tubing, wave propagation analysis, and vibrometric and elastographic measurements using piezoelectric crystal-induced motion. The work completed throughout his project aimed to evaluate the feasibility of integrating the OCT system with Optical Tweezers (OT) and to establish a protocol for further biofilm analysis using this combined optical system.




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